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Secondary Progressive MS (SPMS)

Phase of MS in which disability and symptoms gradually worsen over time.

Secondary progressive multiple sclerosis (SPMS) is a phase of MS in which disability and symptoms gradually worsen over time. SPMS typically follows an initial stage of relapsing remitting multiple sclerosis (RRMS). With SPMS, the frequency of relapses decreases as overall disability and symptom severity gradually increase over time. SPMS can be characterised as ‘active’ (with relapses and/or evidence of new lesions as shown on an MRI scan) or ‘not active’ (without relapses or evidence of lesions as shown on an MRI scan).

References:
MS Society. Secondary- Progressive MS. Available at: https://www.mssociety.org.uk/about-ms/types-of-ms/secondary-progressive-ms. Accessed March 2020

UK | July 2020 | MUL20-C021